Lyme Disease Myths: Separating Fact from Fiction

Written by: MakeWell

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Time to read 3 min

Lyme disease is often surrounded by confusion and misconceptions. As part of our commitment to evidence-based wellbeing, we're addressing common myths about this complex condition. Let's explore what the science really tells us about Lyme disease.

The Complexity of Lyme Diagnosis


Myth: Lyme disease is easy to diagnose with a single blood test.


The reality is more nuanced. The standard two-tiered testing approach (ELISA followed by Western blot) looks for antibodies produced by the body in response to Borrelia burgdorferi bacteria. However, these tests have limitations, particularly during early infection stages when the body may not have produced sufficient antibodies for detection.


Diagnosis often requires a comprehensive approach that considers:


  • Clinical symptoms

  • Physical examination findings

  • History of potential tick exposure

  • Laboratory test results


Myth: A negative Lyme disease test means you definitely don't have Lyme disease.


This is another common misconception. Especially in early infection, tests can return negative results even when the infection is present. If you're experiencing symptoms consistent with Lyme disease and have a history of potential tick exposure, a negative test doesn't necessarily rule out the condition. Healthcare practitioners may consider additional testing or support strategies based on clinical judgment.

Understanding Exposure Risks


Myth: If you don't remember a tick bite, you can't have Lyme disease.


Many individuals with confirmed Lyme disease don't recall a tick bite. This isn't surprising when you consider that tick nymphs (immature ticks) responsible for many Lyme transmissions are extremely small—about the size of a poppy seed. Their bites are typically painless and can easily go unnoticed.



Myth: Lyme disease is only a concern in specific rural areas.


While Lyme disease prevalence varies geographically, infected ticks have been reported in diverse environments, including suburban and even urban settings. Ticks can thrive in various ecosystems, from woodlands to gardens and parks. Awareness is beneficial regardless of where you live or travel.


The Reality of Lyme Experiences


Myth: A short course of antibiotics will cure Lyme disease every time.


While early intervention with appropriate antibiotics is helpful for many people with Lyme disease, the response to treatment can vary between individuals. Research indicates that a percentage of patients may experience ongoing symptoms even after standard antibiotic protocols. The scientific community continues to study the most effective approaches for different presentations of Lyme disease, with ongoing research exploring various factors that may influence treatment outcomes.



Myth: The impact of Lyme disease is exaggerated.


Lyme disease affects individuals differently. For some, it presents with mild symptoms that resolve quickly with appropriate support. For others, it can impact various body systems, including joints, the nervous system, and the heart. While many people recover fully with timely and appropriate care, some may experience longer-lasting challenges.



Myth: Once you've had Lyme disease, you're immune and cannot get it again.


Unfortunately, previous infection with Borrelia burgdorferi doesn't confer lifelong immunity. It's possible to encounter Lyme disease more than once, which highlights the importance of continued awareness and preventive measures even after a previous experience.


Moving Forward with Knowledge About Lyme Disease


Understanding these realities about Lyme disease can help you navigate health information more effectively. Accurate knowledge about Lyme disease testing, symptoms, treatment options, and prevention is essential when discussing this condition with healthcare providers.


At MakeWell, we're committed to providing science-backed information and natural wellbeing solutions that support your individual health journey. Our range of nutritional supplements, developed by experts and rooted in research, is designed to complement your approach to optimal wellbeing.

This article is for informational and educational purposes only. Always consult your healthcare practitioner before starting any new supplement regimen.

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Further Reading


Centers for Disease Control and Prevention (CDC). Testing for Lyme Disease.  https://www.cdc.gov/lyme/diagnostics/index.html


National Institute of Allergy and Infectious Diseases (NIAID). Lyme Disease.  https://www.niaid.nih.gov/diseases-conditions/lyme-disease


Steere, A. C., Strle, F., Wormser, G. P., Hu, L. T., Branda, J. A., Hovius, J. W., & Johnson, L. (2016). Lyme borreliosis. Nature Reviews Disease Primers, 2(1), 1-18.


Aucott, J., Rebman, A. W., Crowder, K., Kortte, K. B., Wills, M. R., Coffin, S., & Smith, E. G. (2009). Post-treatment Lyme disease syndrome. The Journal of the American Medical Association, 301(16), 1703-1710.


Centers for Disease Control and Prevention (CDC). Transmission.  https://www.cdc.gov/lyme/transmission/index.html


Barbour, A. G. (2003). The remarkable life of Borrelia burgdorferi. Annual Review of Microbiology, 57(1), 347-385.


Centers for Disease Control and Prevention (CDC). Where Lyme Disease is Common.  https://www.cdc.gov/lyme/stats/maps.html


Ogden, N. H., & Lindsay, L. R. (2016). Effects of climate and environmental change on Lyme disease in North America. PLoS Medicine, 13(11), e1002165.


Centers for Disease Control and Prevention (CDC). Signs and Symptoms of Untreated Lyme Disease.  https://www.cdc.gov/lyme/signs_symptoms/index.html


Steere, A. C. (2001). Lyme disease. New England Journal of Medicine, 345(2), 115-125.


Centers for Disease Control and Prevention (CDC). Can you get Lyme disease more than once?  https://www.cdc.gov/lyme/faq/index.html


Wormser, G. P., Ramanathan, R., Nowakowski, J., McKenna, D., Holmgren, D., Visintainer, P., Dornbush, R., Singh, B., & Nadelman, R. B. (2003). Duration of antibiotic therapy for early Lyme disease. A randomized, double-blind, placebo-controlled trial. Annals of Internal Medicine, 138(9), 697-704.


Marques, A. (2008). Chronic Lyme disease: a review. Infectious Disease Clinics of North America, 22(2), 341-360.